ABSTRACT
Objective To evaluate the performance of surgical approaches in the treatment of linear scleroderma of the head and face. Methods Forty-three patients with stable linear scleroderma of the head and face were included in this study. Surgical approaches, which included direct suture,skin flap translocation, soft-tissue augmentation and filling operation with dermal tissues, were selected and utilized alone or in combination according to the size, location and degree of atrophy and depression of lesions. Results After surgical treatment, wound dehiscence developed in one of these patients, but the wound healed after two sessions of suture. During one year of follow up, all the patients achieved favorite color, feeling and blood supply in the filling areas as well as good facial profile and visual appearance with no obvious convexity and concavity. Skin flaps matched well with surrounding tissues, incision lines were inconspicuous, and hairline looked naturally with well-distributed hairs in these patients after treatment. Patients were satisfied with treatment results. Conclusion Satisfied cosmetic outcomes can be achieved by using surgical approaches in patients with stable linear scleroderma of the head and face.
ABSTRACT
Inositol,a hexol widely found in nature with a wide range of physiological and biochemical effects,can promote fat metabolism in liver and other tissues and lower blood cholesterol and thus has been used for the clinical treatment of fatty liver, cirrhosis,atherosclerosis and hyperlipidemia. Some derivatives of inositol have been reported to have different biological activities including hypoglycemic,antitussive,anti-inflammatory and other effects. In recent years,its monomethyl ether derivatives,such as pinitol,quebrachitol,and sequoyiol,have been studied widely. In this paper,the bioactivity,extraction,preparation and applications of these monomethyl ether derivatives of inositol are reviewed.